Ruptured silicone breast implants, on the other hand, are usually far less noticeable as leaking silicone often remains trapped in the fibrous tissue around the implant. While this may not cause any long-term disorders or breast cancer, it can lead to breast pain or changes in the shape and size of breasts.
Other issues post-operation include the forming of scar tissues, which causes pain, deformity, and repeated surgeries. The worst possible risk is when the body rejects the implants — which can lead to capsular contracture.
The researchers thus believed they could reduce scar tissue by creating a pattern on the edge of the implant that was more similar to the body’s surface, like the basal layer of skin.
“The surfaces of breast implants in use today have relatively large features on their surface, which have no discernible correlation with biological features required for cells to interact with,” Dr. Ardeshir Bayat of the University’s Institute of Inflammation and Repair said in the press release.
“Importantly, the micro environment created by the features of a breast implant is critical for breast tissue cells to adhere to that surface and grow on.”
The researchers tested the design over the course of a week, which is often a critical time post-surgery.
While more research is needed, they found at least initially that the new surface was able to lower the foreign body reaction of the cells compared to the current smoother surfaces that are used currently. Some of the current surfaces were designed back in the 60s and 70s — meaning they’re quite out of date.
“Compared to the size of the cells, these bumps on existing implants are so large that they’re effectively a smooth cliff face compared to the dimensions required for the cell to interact with,” Bayat said in the press release.
“Our approach was to create a novel surface which mimics the basal layer of the skin, which the body’s cells are more likely to recognize and interact with favorably.” CONTINUE READING
MEDICALDAILY
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