I | INTRODUCTION |
Alcoholism or
Alcohol Dependence, chronic disease marked by a
craving for alcohol. People who suffer from this illness are known as
alcoholics.
They cannot control their drinking even when it becomes the
underlying cause of serious harm, including medical disorders, marital
difficulties, job loss, or automobile crashes.
Medical science has yet to
identify the exact cause of alcoholism, but research suggests that genetic,
psychological, and social factors influence its development.
Alcoholism cannot
be cured yet, but various treatment options can help an alcoholic avoid drinking
and regain a healthy life.
People tend to equate any kind of excessive
drinking with alcoholism. But doctors and scientists recognize that disorders
related to alcohol use lie along a continuum of severity.
They prefer to use the
term alcohol dependence instead of alcoholism to designate the
most severe of the alcohol-use disorders. The terms alcohol abuse and
problem drinking designate less severe disorders resulting from
immoderate drinking.
Alcohol dependence develops differently in each
individual. But certain symptoms characterize the illness, according to the
National Institute on Alcohol Abuse and Alcoholism (NIAAA), a United States
government agency that is part of the National Institutes of Health.
Alcoholics
develop a craving, or a strong urge, to drink despite awareness that drinking is
creating problems in their lives. They suffer from impaired control, an
inability to stop drinking once they have begun.
Alcoholics also become
physically dependent on alcohol. When they stop drinking after a period of heavy
alcohol use, they suffer unpleasant physical ailments, known as withdrawal
symptoms, that include nausea, sweating, shakiness, and anxiety.
Alcoholics develop a greater tolerance for alcohol—that is, they
need to drink increasing amounts of alcohol to reach intoxication. The World
Health Organization (WHO) notes that other behaviors common in people who are
alcohol dependent include seeking out opportunities to drink alcoholic
beverages—often to the exclusion of other activities—and rapidly returning to
established drinking patterns following periods of abstinence.
II | PREVALENCE |
Alcohol dependence affects a broad cross
section of society around the world. Statistics show that alcohol dependence
touches successful business executives, skilled mechanics, laborers, homemakers,
and church members of all denominations.
Scientists have not identified a
typical alcoholic personality, and they cannot predict with absolute certainty
which drinkers will progress to alcohol dependence.
Alcohol use varies depending on an
individual’s social, cultural, or religious background. Some individuals do not
drink at all—about one-third of adults in the United States who are 18 and
older, for example, abstain from alcohol. Others drink as part of social custom.
Still others drink frequently and in substantial amounts. Those suffering from
alcohol dependence drink to appease an uncontrolled craving for alcohol or to
avoid experiencing the unpleasant symptoms of withdrawal.
WHO estimates that about 76 million people
worldwide suffer from alcohol-related disorders. The prevalence of the illness
varies in different countries. In the United States about 15 percent of the
population experiences problems related to their use of alcohol. Of these,
alcohol dependence affects about 12.5 million men and women, or almost 4 percent
of the population. Men are three times more likely than women to become
alcoholics, while people aged 65 and older have the lowest rates of alcohol
dependence.
In the United States, people who start to
drink at an early age are at particular risk for developing alcohol dependence.
Estimates indicate that 40 percent of people who begin to drink before age 15
will become alcohol dependent at some point
in their lives. These individuals
are four times more likely to become alcohol dependent than those who delay
drinking until age 21.
In Canada, an estimated 4 percent of the
people aged 15 and older are alcohol dependent, and the number of male
alcoholics is double that of females. The highest rate of this illness occurs in
Canadians between the ages of 20 and 24. In Canadian surveys about one in five
current and former drinkers admit that their drinking harmed them at some point
in their lives, affecting their jobs or financial position.
Alcohol dependence has reached critical
proportions in Russia, where it is estimated that almost a third of all deaths
are related, directly or indirectly, to alcohol abuse. Periodic efforts by the
government to control drinking by closing distilleries, breweries, and bars have
backfired. Instead of solving the problem, such tactics only created a
widespread black market for liquor—as well as a country of people who hide their
drinking problems.
In Asian nations such as Japan, alcohol abuse
has become a social concern. In these countries, drinking almost is required
when conducting business. Bars are an extension of offices, places where key
decisions are made. A person who declines an invitation to a drink after work
risks being passed over for promotion within the company. Alcohol is readily
available in Japan—vending machines along the streets of Tokyo dispense cans of
beer and sake.
III | PHYSICAL EFFECTS OF ALCOHOL |
Ethyl alcohol, or ethanol, is present in
varying amounts in beers and wines, and in distilled liquors such as whiskey,
gin, and rum. When a person consumes alcohol, the stomach and intestines rapidly
absorb it. From there alcohol travels in the blood throughout the entire body,
affecting nearly every tissue. Moderate and high doses of alcohol depress the
functions of the central nervous system, including the brain. The higher the
alcohol level is in the blood, the greater the impairment.
As blood passes through the liver, enzymes
break down alcohol into harmless byproducts, which are eliminated from the body
six to eight hours later. But the rate at which alcohol accumulates in the body
may be faster than the rate at which the body eliminates it, resulting in rising
alcohol levels in the blood. Consequently, alcohol remains in the body,
producing intoxicating effects hours after the last drink was swallowed.
Small amounts of alcohol may relieve tension
or fatigue, increase appetite, or produce an anesthetic affect that numbs pain.
Larger quantities inhibit or depress higher thought processes, bolstering
self-confidence and reducing inhibition, anxiety, and guilt. As a person becomes
intoxicated, painful or embarrassing situations appear less threatening and, as
drinking progresses, speech may become loud and slurred. Impaired judgment may
lead to incautious behavior, and physical reflexes and muscular coordination may
become noticeably affected. If drinking continues, complete loss of physical
control follows, ending in stupor, and possibly death.
IV | SOCIAL EFFECTS OF ALCOHOLISM |
Throughout most of history, society has
viewed people who drink to excess as irresponsible, immoral, and of weak
character. Punishment of drunkards was considered necessary to protect the
community. By the early 1900s, experts conceded that alcohol dependence may
result from tissue changes caused by the action of alcohol. These changes
produce a continued need to drink, such that the individual seeks larger amounts
of alcohol at more frequent intervals. However, society still regarded taking or
rejecting a drink as a matter of personal decision, thus all excessive drinking
was considered a voluntary act. The individual, therefore, was held responsible
for his or her behavior.
Although a consensus is growing among health
professionals that alcohol dependence is a disease, society’s attitudes toward
individuals with drinking problems remain ambivalent and confused. Until the
mid-20th century, the typical picture of the alcoholic was of someone without
steady employment, unable to sustain family relationships and most likely in
desperate financial straits. But this stereotype was largely dispelled when
highly respected people publicly admitted their alcohol dependence and shared
their successful recovery stories. Particularly critical in changing the way
Americans view alcohol-use disorders were New York broker William Griffith
Wilson (more familiarly known as Bill W.) and Ohio physician Robert Holbrook
Smith (Dr. Bob). In 1935 these two recovered alcoholics developed a program to
promote their successful philosophy for recovering from alcohol dependence. The
program, which became known as Alcoholics Anonymous, has spread around the
world, helping millions of members to avoid alcohol use and rebuild their lives.
In the late 1970s Betty Ford, the wife of former U.S. president Gerald Ford,
disclosed her struggle to recover from alcohol dependence. She helped raise the
public’s understanding about alcohol dependence through her open, honest
revelations and her creation of a groundbreaking treatment center for substance
abusers in Rancho Mirage, California, now known as the Betty Ford Center.
Intoxication threatens not only the
individual who drinks but also the surrounding community. Therefore, societies
around the world have attempted to control excessive use of alcohol. Temperance
societies in the 19th and 20th centuries pushed for laws ranging from arrest and
jail sentences for public drunkenness to prohibition of the manufacture,
distribution, and consumption of alcoholic beverages.
Today experts characterize alcohol-use
disorders as a form of illness, and one so widespread that it constitutes a
major public health problem. According to WHO, alcohol dependence and other
alcohol-use disorders undermine global health, accounting for 3.5 percent of the
total cases of disease worldwide. This figure equals the hazards posed by unsafe
sex and surpasses two other formidable health foes, tobacco and illicit drugs.
In the United States alone, the NIAAA estimates that alcoholism causes losses of
more than $185 billion a year in lost productivity, illness, and premature
death.
V | DEVELOPMENT OF ALCOHOL DEPENDENCE |
Alcohol-use disorders develop in a predictable
pattern. Health professionals use three stages to describe this progression.
Each stage is defined by a set of symptoms that are used in early diagnosis and
treatment. Most individuals who drink alcohol never progress beyond stage one
and are commonly known as social drinkers. In this stage, individuals drink
alcohol primarily as an accompaniment to social situations. Drinking at this
stage is not the central focus of a person’s activities.
A small percentage of social drinkers progress
to stage two. In this early stage of a drinking problem, many people do not show
any signs of illness. But often, more severe problems develop with time and
continued heavy drinking. Activities that focus on drinking may take up
increasingly larger amounts of time in the person’s life, and as problem
drinking progresses the alcoholic’s intoxicated behavior may become disagreeable
and antisocial. A person may resort to drinking to relieve the physical
discomfort of withdrawal symptoms. Most often, attempts to avoid the discomfort
result in morning drinking to offset symptoms that develop after a bout of
drinking the night before.
As drinking continues, drinkers cannot
acknowledge that drinking and intoxication have become goals in themselves.
Drinking may become a technique for coping with problems, many of which have
been brought about by alcohol use. Drinkers may neglect responsibilities to
their family, seriously damaging relationships with their partners and children.
Their productivity at work declines, often resulting in job loss. Despite
numerous negative consequences experienced as a result of their drinking, they
remain in denial about their problem. They continue to claim to friends or
family that they can stop drinking any time they want to. But in actuality they
find it increasingly difficult to control their alcohol use.
Stage three is the final stage of alcohol
dependence. In addition to suffering from many of the problems experienced by
individuals in stage two, an individual in stage three can no longer control his
or her drinking. This impaired control, in which the compulsion to drink is
overwhelming, is the key identifier that health professionals use to diagnose
people who have progressed to alcohol dependence.
VI | CAUSES |
Scientists do not know precisely what causes
alcoholism, but most experts suspect that a combination of factors are involved,
which may explain why some people who drink become alcohol dependent while most
do not.
A | Physiological Causes |
Scientists have explored the chemical
action of alcohol among both normal individuals and individuals who suffer from
alcohol-use disorders, particularly alcohol dependence. Some studies suggest
that some people may have a physical trait that enables them to drink large
quantities of alcohol before feeling its intoxicating effects. These people have
an enhanced tolerance for alcohol. Scientists are unsure if this trait causes
excessive drinking or develops as the result of such drinking.
Studies show that alcoholism runs in
families—alcoholics are six times more likely than nonalcoholics to have blood
relatives who are alcohol dependent. Researchers have long pondered whether
these familial patterns result from genetics or from a common home environment,
which often includes alcoholic parents. Studies of twins attempt to identify if
alcohol dependence develops as the result of genetic factors, shared
environmental influences, or a combination of both. Laboratory studies compare
the genetic structure in people who are alcohol dependent with those who have no
personal or family history of the disease.
Studies of twins in the 1980s showed that
patterns of alcohol dependence differed among identical twins, who share
identical genes, and fraternal twins, who are genetically different. If one twin
becomes alcohol dependent, an identical twin is more likely to develop alcohol
dependence than a fraternal twin. While these studies suggest that a genetic
factor plays a role in alcohol dependence, the results are difficult to
interpret. Many of these studies assumed that all twins share a similar home
environment. But more recent studies revealed that the home environments of
identical twins are more alike than the environments of fraternal twins. That
is, as children, identical twins are more likely than fraternal twins to play
and study together and to share friends. And as adults, identical twins are more
likely than fraternal twins to stay in close contact with each other, possibly
resulting in the development of similar behaviors. Scientists are conducting
further twin studies that take into account differences in home environments.
Scientists now recognize that alcoholism is
a polygenic disease—that is, many genes are involved in increasing an
individual’s risk for developing alcohol dependence. In addition to family
studies that establish a broad genetic influence on alcoholism, scientists
perform laboratory studies to try to identify the specific genes involved in the
development of alcohol dependence. One method scientists use is to look for
genetic markers related to alcoholism. A genetic marker is a gene that produces
an observable trait and has a known location on a chromosome, the rod-shaped
structures that carry genes. Once scientists have identified genetic markers,
they attempt to determine if the markers are inherited in people with
alcoholism. If the marker is inherited along with alcoholism, scientists know
that the genes that cause alcoholism are likely located close to the genetic
marker on the chromosome.
In 1998 researchers moved closer to the
goal of finding the genes for alcoholism when they identified locations on four
chromosomes where these genes are likely to be. Some experts speculate that
these genes may not be specific for alcohol dependence, but rather may determine
temperament or personality traits that increase a person’s vulnerability to
alcohol-use disorders.
B | Environmental Causes |
Scientists recognize that alcohol-use
disorders likely results from a complex interaction of biological influences and
environmental factors. Environmental factors that may affect the development of
the disease include personal behavioral skills, peer influences early in life,
parental behavior, societal and cultural attitudes toward alcohol use, life
stress, and availability of alcoholic beverages. Once a person has established a
drinking pattern, environmental factors combined with physical changes induced
by heavy drinking may reinforce the continued use of alcohol.
C | Psychological Influences |
Many experts believe that a loss of
control over drinking is as much psychological as it is physiological. Studies
show that alcohol-dependent individuals will drink excessive amounts of a
nonalcoholic beverage if they believe it contains alcohol. Moreover, when they
are given an alcoholic beverage that they believe is alcohol-free, their
drinking behavior is similar to that of persons not dependent on alcohol.
Many drinkers develop a psychological
condition known as denial, in which they are unable to acknowledge that alcohol
use lies at the root of many of their problems. Denial was long thought to be a
personality trait shared by all persons who suffer from alcohol-use disorders.
Recent research suggests that denial may be a psychological response to negative
feedback people receive about their drinking. Some studies indicate that when
approached with objective information about their drinking and its consequences
in an empathetic and nonconfrontational manner, many persons with significant
drinking problems do not demonstrate denial.
VII | HEALTH CONSEQUENCES |
While some studies have found that moderate
use of alcohol has beneficial health effects, including protection from coronary
heart disease, heavy and prolonged intake of alcohol can seriously disturb body
chemistry. Heavy drinkers lose their appetite and tend to obtain calories from
alcohol rather than from ordinary foods. Alcohol is rich in calories and can
provide substantial amounts of energy. However, if it constitutes the primary
source of calories in place of food, the body will lack vitamins, minerals, and
other essential nutrients.
Prolonged use of large amounts of alcohol
may cause serious liver damage. In the first stage of liver disease caused by
alcohol, fat accumulates in the liver. This stage of the disease is known as
fatty liver. Most people do not notice symptoms of fatty liver, although in some
people the liver becomes enlarged and tender. Some people with fatty liver
develop hepatitis, which inflames and kills liver cells. Hepatitis is marked by
jaundice, which gives a yellowish tint to the eyes and skin. Others may develop
cirrhosis, an irreversible condition in which normal liver tissue is replaced by
scar tissue. The scarring prevents blood from traveling freely through the
liver, building blood pressure in the veins that run from the intestine to the
liver. Consequently, the liver can no longer process toxins efficiently, causing
poisons to build up in the blood. This buildup can be fatal.
Heavy drinking also damages heart muscle.
Nearly half of all cases of cardiomyopathy are caused by alcohol abuse. In this
heart disease, the heart muscles, particularly the right and left ventricles,
enlarge and become flabby, reducing the heart’s blood-pumping efficiency. This
inefficiency reduces the flow of blood through the kidneys, which normally
filter excess salts and water out of the blood. Eventually the blood volume
rises, causing a potentially fatal backup of fluid in the lungs.
Alcoholics tend to have high blood levels
of the hormone epinephrine and deficiencies of the mineral magnesium. This
combination produces severe arrhythmias, or heartbeat irregularities, a common
cause of sudden death in heavy drinkers. Chronic drinkers typically develop
hypertension, a leading cause of stroke.
In some cases, alcohol withdrawal may lead
to delirium tremens (DTs), which produces increasing confusion, sleeplessness,
depression, and terrifying hallucinations. As this delirium progresses, the
hands develop a persistent and uncontrollable shaking that may extend to the
head and body.
Women who drink excessive amounts of
alcohol while pregnant run a high risk of having a baby born with fetal alcohol
syndrome (FAS), the leading known cause of birth defects. FAS results in a
combination of mental and physical defects, such as retardation, a small head,
and poor muscle tone. Some babies exposed to alcohol during fetal maturation
develop fetal alcohol effect (FAE), which produce more subtle symptoms,
including behavioral problems, difficulty paying attention, or the inability to
think abstractly.
VIII | TREATMENT |
The best methods to treat alcohol
dependency vary, depending upon an individual’s medical and personal needs. Some
heavy drinkers who recognize their problem appear to recover on their own.
Others recover through participation in the programs of Alcoholics Anonymous or
other self-help groups. Some alcoholics require long-term individual or group
therapy, which may include hospitalization. And still others do not seek
treatment at all. These people do not seek treatment as the result of a
combination of factors, including ignorance of the symptoms of alcohol-use
disorders, the social stigma that still surrounds these disorders—that is, the
fear of being labeled an alcoholic—and an unwillingness to accept lifetime
abstinence from alcohol as a treatment goal.
Numerous studies indicate that simple,
brief interventions can be effective in changing drinking behavior in those who
are not severely alcohol dependent. In brief interventions, a problem drinker
meets with a health professional for one to four sessions, with each session
lasting from a few minutes to an hour. During these meetings, the health
professional makes the person aware that his or her current drinking patterns or
medical problems are related to alcohol abuse and could progress to alcohol
dependence. Using a warm, reflective, and understanding style of delivery, the
health professional employs a variety of strategies to encourage the individual
to change his or her drinking behavior. The goal of brief interventions
typically is to help people moderate their drinking rather than resort to
complete abstinence. Brief interventions also have been used to motivate
alcoholics to enter specialized treatment programs and work toward complete
abstinence from alcohol.
For some alcoholics, treatment begins with
detoxification, which safely rids the patient’s body of alcohol while treating
any physical complications that develop from severe withdrawal symptoms, such as
delirium tremens. Detoxification normally requires less than a week, during
which time patients usually stay in a specialized residential treatment facility
or a separate unit within a general or psychiatric hospital. These facilities
also offer extended treatment programs to help alcoholics in their recovery
effort.
Recovery also may involve individual
counseling and group therapy to help a person who is alcohol dependent adapt to
a new way of life, one that is not driven by alcohol. Throughout the United
States and Canada, public outpatient and inpatient clinics offer a variety of
treatments for alcoholics. The National Council on Alcoholism and Drug
Dependence (NCADD) has affiliates in many cities that help people who are
alcohol dependent find appropriate treatment programs. Many public mental
hospitals and Veterans Administration hospitals, as well as private clinics and
hospitals, treat alcohol dependence.
Physicians may prescribe medications to
help prevent alcoholics from returning to drinking once they have stopped. The
drug disulfiram (sold under the trade name Antabuse), interferes with the
way the body processes alcohol. Taken in pill form daily, this medication
generally has no noticeable effects until a person drinks alcohol. The alcohol
and drug interact to produce an extremely unpleasant reaction, including nausea,
dizziness, headache, heart palpitations, and other problems. Alcoholics then
associate illness with drinking and, in many cases, avoid alcohol use.
Naltrexone (ReViva) is a narcotic approved for use in alcohol treatment
in 1995. Although scientists are not certain how this medication works in the
brain, it reduces an alcoholic’s craving for alcohol, most likely by blocking
the positive effects the individual gets from drinking alcohol. Naltrexone is
most effective when it is used in combination with counseling programs.
Acamprosate (trade name, Campral) is used to help alcoholics maintain
abstinence once they have ceased drinking. Scientists believe it works by
restoring balance among the chemicals that enable brain cells to communicate
with one another. Alcohol dependence disrupts this balance.
Most treatment programs effectively help
alcohol-dependent persons stop drinking for a period, but they are less
successful in preventing a subsequent return to drinking. Treatment programs
typically contain a component that focuses on helping alcoholics understand the
situations, feelings, and interpersonal interactions that trigger drinking.
These programs teach people how to cope with these factors without returning to
drinking.
In addition to formal treatment programs,
other widely available community resources include vocational rehabilitation,
family guidance, and religious counseling. Many countries, including Poland,
Finland, and South Africa, and some U.S. states have compulsory treatment
programs for alcoholics who have committed crimes. Mutual-help organizations,
such as Alcoholics Anonymous and Rational Recovery, provide a free and effective
method to cope with recovery.
A | Alcoholics Anonymous |
Until the mid-1930s, alcohol-dependent
individuals who could not afford a private sanitarium or psychiatrist could find
help only at state hospitals, in jails, or through street ministries. The
formation of Alcoholics Anonymous (A.A.) in 1935 marked the first nonmedical
approach that made sustained recovery from alcohol dependence possible for many
individuals. Today nearly 2 million people worldwide claim membership in
A.A.
The A.A. program promotes psychological
principles that help people live a healthy, stress-free lifestyle. The
organization functions through local groups that have no constitutions,
officers, or dues. Anyone who has a drinking problem may become a member,
provided he or she is willing to abstain from alcohol and make an honest attempt
to live by the principles outlined by the organization.
In A.A. meetings the individual learns
that he or she suffers from a disease. Any feelings of unworthiness the
individual feels are dispelled by supportive group interaction. A.A. offers a
twelve-step program to recovery. The twelve-step program confronts the problem
of denial by urging alcoholics to admit that their drinking has made their lives
unmanageable. The program also calls for alcoholics to atone for the harm caused
by their alcoholism, to commit themselves to live ethically and spread the A.A.
message to others, and to rely on a higher power greater than their own will.
Mutual help groups for family members of alcoholics include Alateen, which
serves teenagers, and Adult Children of Alcoholics. Al-Anon is a mutual help
group open to friends and family of alcoholics (see Al-Anon Family
Groups).
B | Other Recovery Approaches |
While Alcoholics Anonymous is widely
recognized as an effective source of support, not everyone responds to the
group’s spiritual bent. Other recovery approaches include national organizations
such as Rational Recovery and Secular Organizations for Sobriety/Save Our Selves
(SOS).
Rational Recovery was developed in 1986
for people who find the A.A. approach unappealing. Rational Recovery promotes
lifelong abstinence from alcohol and teaches people how to recognize what is
called an addictive voice, the thoughts and feelings that promote alcohol use.
By identifying the addictive voice and separating from it, people seeking to
avoid alcohol can learn to avoid the actions the addictive voice
instigates.
Secular Organizations for Sobriety/Save
Our Selves (SOS) uses peer-group support to promote abstinence. In these support
sessions, recovery is separated from spirituality—individuals are encouraged to
rely on themselves and others in the group, not a spiritual power, to gain
sobriety. LifeRing is another organization that uses support groups and a
secular philosophy to help people overcome their problems with alcohol.
IX | PREVENTION OF ALCOHOL DEPENDENCE |
A concerted effort by many public health
organizations may in time enable society to readily identify early signs of
problem drinking and encourage people to accept early intervention before the
condition worsens. Many agencies seek to improve public understanding about this
illness, including the NIAAA, the Substance Abuse and Mental Health Services
Administration, the National Clearinghouse on Alcohol and Drug Information,
Health Canada, and the Canadian Center on Substance Abuse. Advertising
campaigns, newspaper articles, feature stories in magazines, and motion picture
and television presentations that call attention to the problem help lessen any
social stigma still attached to the disease. Schools and colleges sponsor
programs that help students to recognize the symptoms of alcohol dependence and
to know how to get help when drinking becomes a problem. As the public becomes
more aware of the health and social consequences of the disease, the incidence
of alcohol dependence may decrease, and earlier and better treatments may lead
to higher recovery rates.
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