Sperm
The term sperm is derived from the Greek word sperma (meaning "seed") and refers to the male reproductive cells. In the types of sexual reproduction known as anisogamy and oogamy, there is a marked difference in the sizeof the gametes with the smaller one being termed the "male" or sperm cell.
A uniflagellar sperm cell that is motile is referred to as a spermatozoon, whereas a non-motile sperm cell is referred to as a spermatium. Sperm cells cannot divide and have a limited life span, but after fusion with egg cells during fertilization, a new organism begins developing, starting as a totipotent zygote.
The human sperm cell is haploid, so that its 23 chromosomes can join the 23 chromosomes of the female egg to form a diploid cell. In mammals, sperm develops in the testicles and is released from the penis. It is also possible to extract sperm throgh TESE.
Sperm in animals
Anatomy
The mammalian sperm cell consists of a head, a midpiece and a tail. The head contains the nucleus with densely coiled chromatin fibres, surrounded anteriorly by an acrosome, which contains enzymes used for penetrating the female egg. The midpiece has a central filamentous core with many mitochondria spiralled around it, used for ATP production for the journey through the female cervix, uterus and uterine tubes. The tail or "flagellum" executes the lashing movements that propel the spermatocyte.During fertilization, the sperm provides three essential parts to the oocyte: (1) a signalling or activating factor, which causes the metabolically dormant oocyte to activate; (2) the haploid paternal genome; (3) the centrosome, which is responsible for maintaining the microtubule system.
Origin
The spermatozoa of animals are produced through spermatogenesis inside the male gonads (testicles) via meiotic division. The initial spermatozoon process takes around 70 days to complete. The spermatid stage is where the sperm develops the familiar tail. The next stage where it becomes fully mature takes around 60 days when its called a spermatozoan.[2] Sperm cells are carried out of the male body in a fluid known as semen. Human sperm cells can survive within the female reproductive tract for more than 5 days post coitus.[3] Semen is produced in the seminal vesicles, prostate gland and urethral glands.Sperm quality
Sperm quantity and quality are the main parameters in semen quality, which is a measure of the ability of semen to accomplish fertilization. Thus, in humans, it is a measure of fertility in a man. The genetic quality of sperm, as well as its volume and motility, all typically decrease with age.[4] (See paternal age effect.)Market for human sperm
On the global market, Denmark has a well-developed system of human sperm export. This success mainly comes from the reputation of Danish sperm donors for being of high quality and, in contrast with the law in the other Nordic countries, gives donors the choice of being either anonymous or non-anonymous to the receiving couple.Furthermore, Nordic sperm donors tend to be tall and highly educated and have altruistic motives for their donations, partly due to the relatively low monetary compensation in Nordic countries. More than 50 countries worldwide are importers of Danish sperm, including Paraguay, Canada, Kenya, and Hong Kong.
However, the Food and Drug Administration (FDA) of the US has banned import of any sperm, motivated by a risk of mad cow disease, although such a risk is insignificant, since artificial insemination is very different from the route of transmission of mad cow disease. The prevalence of mad cow disease is one in a million, probably less for donors. If prevalence was the case, the infectious proteins would then have to cross the blood-testis barrier to make transmission possible.
Healthy Sperm
A healthy male discharges 50 million sperm in a single ejaculation. During sexual intercourse, of all those millions of sperm, only a couple hundred will make it to a mature egg that is ready to be fertilized.
Factors That May Affect Sperm Health
It is important to remember that there is still a lot to learn about male fertility. We do know that a lot of the things that make sperm healthy are the things that are healthy for men anyway. Keep in mind, though, that the following tips are merely considerations for men with potential fertility problems.Many men have no problem with their sperm count, no matter their lifestyles.
Remember, you should discuss any fertility problems with your doctor to evaluate an underlying cause.
- Tight trousers and underwear, synthetic material and heat: It has been suggested that all these adversely affect fertility, so get out those baggy cotton boxers! Keep the family jewels cool. It is known that the testes function most effectively (including the production of sperm) at slightly cooler than core body temperature.
- Geography: One study showed that geographic location influenced average sperm count. Men in New York City had higher sperm counts than men in Los Angeles. (Whether a man's sperm count will increase should he move from L.A. to the Big Apple is not clear, however.)
- Hot tubs and saunas: Frequent use of hot tubs and saunas may lower sperm counts, as heat may decrease sperm production.
- Alcohol: Alcohol consumption can damage sperm production in a couple of ways. First, it may increase the production of estrogen by the liver, which can lower sperm count. Also, alcohol can directly poison the sperm-producing cells of the testicle. Limit your alcohol intake when you are trying to improve your fertility.
- Drugs: There are a number of drugs that affect male fertility, including steroids, cytotoxic drugs used in cancer treatments, and opiates. Contact your family doctor if you are on any long-term medication that you are worried may affect your fertility. Doctors should always inform you of any side effects, but it is always easy to check if you have forgotten.
- Environmental toxins: There is quite a lot of conflicting evidence about environmental substances that may cause damage to sperm. It is known that radiation causes damage and birth defects. Other substances thought to have a detrimental effect on sperm are some perfumes containing phthalates, some types of pesticides, organic mercury, polychlorinated biphenyls, and estrogens in water supply. Many of these substances are still the subject of ongoing research.
- Smoking: Smokers have been shown to have diminished fertility compared to non-smokers. Smoking may adversely affect the sperm's movement, as well as the health of the sperm.
- Time of day: Sperm counts are higher in the morning.
- Excessive ejaculation and prolonged abstinence: Both are known to affect the number and quality of sperm. Intercourse every 2 to 3 days helps ensure optimal sperm count and health.
- Diet: A healthy balanced diet is important. Foods rich in antioxidants may promote optimal sperm health.
- Supplements: Folic acid, selenium, and zinc sulfate have been shown to improve sperm counts and sperm function.
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